My favorite series of books is based on this – David Brin’s Uplift series. In this book we have genetically engineered dolphins and monkeys to be sentient along with us!
Is it possible, in theory yes. There are obvious ethical complications to this. It also depends on what we mean by sentience. We have trained some chimpanzees to communicate using sign language and researchers are able to have full conversations with them. Mostly about bananas though I imagine 😛
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